Bioequivalence and Dose Proportionality of Inhaled Fluticasone Furoate
نویسندگان
چکیده
Abbreviations: AE: Adverse Event; AUC(0-t’): Area Under the Curve from Zero (Pre-Dose) to the Time of Last Common Measurable Time Point Within Subject; BLQ: Below the Limit of Quantitation; CI: Confidence Interval; Cmax: Maximum Plasma Concentration; COPD: Chronic Obstructive Pulmonary Disease; CV: Coefficient of Variation; DPI: Dry Powder Inhaler; FF: Fluticasone Furoate; FP: Fluticasone Propionate; ICS: Inhaled Cortisosteroid; KEDTA: Tri-potassium Ethylene Diamine Tetra-acetic Acid; LABA: Long Acting BetaAgonist; MAT: Mean Absorption Time; NA: Not Applicable; t’: Time of Last Common Measurable Time Point Within a Subject; tmax: Time to Maximum Observed Concentration; VI: Vilanterol; VPC: Visual Predictive Check
منابع مشابه
Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma
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